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ZOLOFT DRUG INFORMATION, ABOUT ZOLOFT®

WHAT IS ZOLOFT?

Zoloft is used to treat panic attacks, depression, obsessive compulsive disorders (OCD), and post-traumatic stress disorder (PTSD). Zoloft works to help restore balance to certain natural chemicals in the brain.

Zoloft is also used to treat a severe form of premenstrual syndrome (premenstrual dysphoric disorder- PMDD) and sexual problems in men (premature ejaculation).

HOW TO USE

Take Zoloft tablets by mouth, usually once daily. Take with or without food (or as directed by your medical provider).

It is best to take your dosage at the same time each day. Take Zoloft either in the morning or in the evening.

The dosage varies based on your medical condition and your response to therapy.

It is important to continue taking Zoloft as prescribed even if you feel better.

It may take up to 4 weeks before the full benefit of Zoloft takes effect.

Do not stop taking Zoloft without consulting with your doctor.

ZOLOFT SIDE EFFECTS

If any of these Zoloft side effects continue or get worse, notify your doctor.

• diarrhea
• dizziness
• drowsiness
• dry mouth
• headache
• trouble sleeping
• nausea
• upset stomach

Tell your medical provider immediately if any of these serious Zoloft side affects occur:

• appetite loss
• decreased interest in sex
• fatigue - unusual
• mental/mood changes - unusual or severe
• sweating/flushing - increased
• tremor - uncontrolled movements
• weight loss - unusual

Tell your doctor immediately if any of these unlikely but serious Zoloft side effects occur:

• changes in sexual ability
• vision changes
• painful and/or prolonged erection

Tell your medical provider immediately if any of these highly unlikely but very serious Zoloft side effects occur:

• chest pain
• fainting
• irregular heartbeat
• muscle pain
• ringing in the ears
• seizures
• trouble swallowing

An allergic reaction to Zoloft is unlikely, however, seek immediate medical attention if it occurs. Symptoms of an allergic reaction:

IMPORTANT NOTE: This information is supplemental only, not a substitute for, the judgment and expertise of your physician, pharmacist or other healthcare professional. It should not be taken to indicate that use of the drug is effective, safe or appropriate for you. Consult your healthcare provider before this medicine is used

• breathing trouble
• dizziness - severe
• itching
• rash
• swelling

If you notice other side effects not listed, contact your doctor or pharmacist.

PRECAUTIONS

Your doctor needs to know your medical history, especially:

• seizures
• heart problems
• liver problems
• kidney disease
• any allergies

Zoloft may make you dizzy or drowsy. Use caution if mental alertness is needed, such as driving or using machinery.

Limit alcoholic beverage consumption.

The elderly may be more sensitive to the effects of Zoloft. Caution is advised.

ZOLOFT and PREGNANCY

During pregnancy, Zoloft should be used only when clearly needed. Discuss the risks and benefits with your medical provider.

ZOLOFT and BREAST FEEDING

Zoloft passes into breast milk. Because of the potential risk to the baby, breastfeeding while using it is not recommended. Consult your medical provider before breastfeeding.

ZOLOFT DRUG INTERACTIONS

Serious, even fatal, drug interactions with certain medications taken with Zoloft may occur.
For 2 weeks before or after taking Zoloft, avoid taking MAO inhibitors, for example:

• linezolid
• furazolidone
• moclobemide
• isocarboxazid
• selegiline
• phenelzine
• tranylcypromine
• procarbazine

Consult your doctor or pharmacist for more information.

Zoloft is not recommended for use with:

• weight loss drugs, for example
  • sibutramine
  • phentermine
• terfenadine
• astemizole

Ask your doctor or pharmacist for more information.

Tell your doctor of all the medication you use, prescription and nonprescription, especially:

• other SSRI antidepressants, for example:
  • fluoxetine
  • citalopram
    
    
• nefazodone
• "triptan" migraine drugs, for example
  • sumatriptan
  • zolmitriptan
    
    
• tramadol
• venlafaxine
• tricyclic antidepressants, for example:
  • amitriptyline
  • nortriptyline
    
    
• cimetidine
• clozapine
• flecainide
• lithium
• blood thinners, for example
  • warfarin
    
    
• any herbal/natural products, for example
  • ayahuasca
  • melatonin
  • St. John's wort
    
    
• propafenone
• trazodone
• tryptophan

Tell your doctor if you use drugs that may cause drowsiness, for example:

• anti-anxiety drugs (e.g., diazepam)
• certain antihistamines (e.g., diphenhydramine)
• anti-seizure drugs (e.g., carbamazepine)
• sleep medicine
• sedatives
• tranquilizers
• narcotic pain relievers (e.g., codeine)
• muscle relaxants
• psychiatric medicines (e.g., phenothiazines such as chlorpromazine)

Tell your doctor if you take drugs which affect the heart rhythm (QTc prolongation), for example:

• procainamide
• dofetilide
• pimozide
• quinidine
• sotalol
• sparfloxacin
• diuretics, for example:
  • furosemide
  • hydrochlorothiazide

Ask your doctor or pharmacist for more information.

Do not start or stop taking Zoloft without doctor or pharmacist approval.

ZOLOFT OVERDOSE

If a Zoloft overdose is suspected, contact your local poison control center (1-800-222-1222) or emergency room (911) immediately. Symptoms of overdose may include:

• fainting
• irregular heartbeat
• lightheadedness
• severe dizziness

NOTES

Do not share Zoloft with others.

Your doctor may perform laboratory and/or medical tests monitor your progress.

MISSED DOSE

If you miss a dose, take the dose as soon as you remember. If it is almost time for the next dose, skip your missed dose. Then resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE

Store Zoloft at room temperature between 59 and 86 degrees F (15 and 30 degrees C) Keep away from light and moisture. Do not store in the bathroom.

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