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PROZAC DRUG INFORMATION, ABOUT PROZAC

WHAT IS PROZAC?

Prozac is used to treat:

• depression
• obsessive compulsive disorders
• bulimia
• severe symptoms of premenstrual syndrome (premenstrual dysphoric disorder-PMDD)

Prozac works by helping restore balance to certain natural chemicals found in the brain.

OTHER PROZAC USES

Prozac has also been used to treat

• alcoholism
• obesity
• panic attacks

HOW TO USE PROZAC

Take Prozac orally (by mouth) once a day in the morning, with or without food; or as directed by your physician.

Dosage is based on your medical condition and on your response to therapy. Some medical conditions may require different dosing schedules (twice a day in the morning and at noon, for example) as determined by your doctor.

Take Prozac exactly as prescribed. It is important to continue taking your medication even if you feel better.

Do not stop taking Prozac without consulting your doctor.

It may take up to four weeks before the full benefit of Prozac is felt.

PROZAC SIDE EFFECTS

If any of these Prozac side effects persist or worsen, notify your doctor promptly:

• drowsiness
• dry mouth
• headache
• nausea
• trouble sleeping
• sweating
• upset stomach

Tell your doctor immediately if any of these serious Prozac side effects occur:

• appetite loss
• decreased interest in sex
• flu-like symptoms (such as, fever, chills, muscle aches, weakness)
• unexplained weight loss
• unusual or severe mood or mental changes
• uncontrolled movements (tremor)

Tell your doctor immediately if any of these serious (although, unlikely) Prozac side effects occur:

• changes in sexual ability
• painful and/or prolonged erection
• difficulty swallowing
• vision changes
• white spots or swelling on your mouth and/or tongue

Tell your doctor immediately if any of these very serious (although, highly unlikely) Prozac side affects occur:

• fainting
• rapid or irregular heartbeat

An allergic reaction to Prozac is unlikely, but if it occurs, seek immediate medical attention. Symptoms of an allergic reaction include:

• trouble breathing
• dizziness
• rash
• itching
• swelling

If you notice other side effects not listed above, contact your doctor.

PROZAC PRECAUTIONS

Tell your doctor your medical history, especially of:

• diabetes
• heart problems
• kidney disease
• liver problems
• seizures
• allergies

Prozac may make you drowsy or dizzy. Use caution when engaging in activities requiring alertness, such as driving, using machinery, etc.

Limit alcoholic consumption.

Liquid preparations of Prozac may contain small amounts of alcohol and/or sugar. This is important to take into consideration if you have alcohol dependence, diabetes or liver disease.

IN THE ELDERLY: Caution is advised when using Prozac in the elderly since they may be more sensitive to the effects of this drug.

PROZAC and PREGNANCY

Prozac should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your physician.

PROZAC and BREAST FEEDING

Prozac passes into breast milk. Because of the potential risk to the infant, breast-feeding while using Prozac is not recommended. Before breast-feeding, consult your doctor.

PROZAC DRUG INTERACTIONS

Certain medications taken with Prozac could result in serious, even fatal, drug interactions.

Before or after treatment with Prozac:

• Avoid taking MAO inhibitors within 2 weeks, e.g.:
  
  
  • linezolid
  • furazolidone
  • moclobemide
  • selegiline
  • isocarboxazid
  • tranylcypromine
  • procarbazine
  • phenelzine
    
    
• Avoid taking thioridazine within 5 weeks.

Consult your physician or pharmacist for additional information.

Prozac is not recommended for use with:

• thioridazine
• terfenadine
• astemizole
• weight loss medicine (e.g., sibutramine, phentermine)

Tell your physician about all prescription and nonprescription (over-the-counter) medicines you use, especially:

• other SSRI antidepressants (e.g., sertraline, citalopram)
• anti-seizure drugs (e.g., phenytoin/hydantoins, carbamazepine)
• blood thinners (e.g., warfarin)
• nefazodone
• clozapine
• flecainide
• haloperidol
• herbal/natural products (e.g., ayahuasca, St John's wort)
• lithium
• propafenone
• trazodone
• triptan migraine medication (e.g., zolmitriptan, sumatriptan)
• tramadol
• tricyclic antidepressants (e.g., nortriptyline, amitriptyline)
• tryptophan
• venlafaxine

Tell your physician if you take any medications that cause drowsiness such as:

• anti-anxiety drugs (e.g., alprazolam)
• certain antihistamines (e.g., diphenhydramine)
• muscle relaxants
• narcotic pain medicine (e.g., codeine)
• psychiatric medicine (e.g., phenothiazines such as chlorpromazine)
• sleep aids
• tranquilizers

Check the labels on all your medicine because they may contain ingredients which cause drowsiness (e.g., cough-and-cold products).

Tell your physician about other medicines you take which affect your heart rhythm (QTc prolongation), like:

• dofetilide
• diuretics ("water pills," such as hydrochlorothiazide or furosemide)
• pimozide
• procainamide
• quinidine
• sparfloxacin
• sotalol

Prozac may affect the amount of sugar in your blood. If you take any medication for diabetes (e.g., glipizide, metformin, glyburideyour), your dosage of these medications may need to be adjusted when Prozac is started or stopped.

Consult your doctor. Do not start or stop Prozac or any medicine without doctor or pharmacist approval.

PROZAC OVERDOSE

If a Prozac overdose is suspected, immediately call the poison control center at (1-800-222-1222). Or call emergency services at (911).

Symptoms of an overdose may include:

• severe dizziness
• lightheadedness
• fainting
• irregular heartbeat

PROZAC NOTES

Do not share Prozac with others.

Your doctor may order laboratory or other medical tests to monitor your progress.

MISSED PROZAC DOSE

If you miss a Prozac dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the dose that was missed. Resume your usual schedule. Do not take a double dose.

PROZAC STORAGE

Store Prozac at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from light and moisture.

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