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Paxil is used to panic attacks, treat depression, social anxiety disorder (social phobia), obsessive compulsive disorders (OCD), and generalized anxiety. This medicine works by helping to rebalance certain natural chemicals in the brain.


Prescription Paxil can also be used to treat a severe form of premenstrual syndrome (premenstrual dysphoric disorder- PMDD), sexual problems in men (premature ejaculation), chronic headaches, nerve problems which may accompany diabetes (diabetic neuropathy), or post-traumatic stress disorder (PTSD).


  • Paxil is taken by mouth usually once a day in the morning.
  • Taken with or without food
  • Or taken as directed by your doctor.
  • Dosage varies depending on your medical condition and response to therapy.
  • Be sure to continue taking this medicine as prescribed by your doctor, even if you feel fine.
  • Do not stop taking Paxil without consulting your doctor. It may take several weeks before the full beneficial effects of the drug are felt.


Inform your doctor if any of these side effects worsen of become bothersome:

  • constipation
  • dry mouth
  • diarrhea
  • dizziness
  • drowsiness
  • nausea
  • trouble sleeping

Promptly inform your doctor if you experience any of these serious side effects:

  • decreased interest in sex
  • loss of appetite
  • unusual fatigue
  • unusual or severe mental/mood changes
  • increased sweating/flushing
  • uncontrolled movements (tremor)

These side effects are unlikely, but promptly inform your doctor if you experience any of them:

  • blurred vision
  • change in amount of urine
  • painful and/or prolonged erection
  • changes in sexual ability

These side effects are highly unlikely, but immediately inform your doctor if you experience any of them:

  • easy bruising or bleeding
  • fainting
  • irregular heartbeat
  • muscle pain
  • seizures
  • tingling or numbness of the hands/feet
  • trouble swallowing
  • unusual swelling

Although an allergic reaction to Paxil is unlikely, but seek immediate medical attention it occurs. Symptoms of an allergic reaction to Paxil include

  • itching
  • rash
  • severe dizziness
  • swelling
  • trouble breathing

If you notice other side effects not listed here, contact your doctor or your pharmacist.


This information is intended to be supplemental only and not a substitute for the expertise and judgment of your pharmacist, doctor or other healthcare professional. It should not be seen as an indication that use of the medication is appropriate, safe or effective for you. Consult your doctor or healthcare professional before this medicine is used


Your doctor needs to know your medical history. Especially tell him or her about:

  • liver problems
  • kidney problems
  • seizures
  • heart problems
  • other mental/mood disorders (e.g., bipolar disorder)
  • thyroid problems
  • any allergies

Paxil may make you drowsy or dizzy. Be careful if you are engaging in activities requiring alertness such as using machinery or driving.

Limit alcoholic consumption.

In the elderly caution is advised when using Paxil. They may be more sensitive to the effects.


During pregnancy, Paxil should be used only when clearly needed. Discuss the risks and benefits with your health care provider.


Consult your doctor before breast-feeding. Paxil passes into breast milk. Because of the potential risk to the baby, breast-feeding while using Paxil is not recommended.


Certain medications taken with Paxil could result in serious, possibly fatal, drug interactions.

Two weeks before or after taking Paxil, avoid taking MAO inhibitors,for example:

  • furazolidone
  • isocarboxazid
  • linezolid
  • moclobemide
  • phenelzine
  • procarbazine
  • selegiline
  • tranylcypromine

Five weeks before or after taking Paxil, avoid taking:

  • thioridazine

Consult your health care professional or pharmacist for additional information.

Paxil is not recommended for use with:

  • weight loss drugs (e.g., sibutramine, phentermine)
  • thioridazine
  • terfenadine
  • astemizole.
  • Inform your doctor of all prescription and nonprescription medicines you may use, especially:
  • other SSRI antidepressants (e.g., citalopram, fluoxetine)
  • blood thinners (e.g., warfarin)
  • cimetidine
  • clozapine
  • digoxin
  • flecainide
  • lithium
  • nefazodone
  • theophylline
  • propafenone
  • tricyclic antidepressants (e.g., nortriptyline, amitriptyline)
  • tramadol
  • triptan migraine drugs (e.g., zolmitriptan, sumatriptan)
  • trazodone
  • tryptophan
  • venlafaxine
  • herbal/natural products (e.g., melatonin, ayahuasca, St John's wort)

Inform your doctor if you take any medinines that cause drowsiness such as:

  • anti-anxiety drugs (e.g., diazepam)
  • anti-seizure drugs (e.g., carbamazepine)
  • certain antihistamines (e.g., diphenhydramine).
  • muscle relaxants
  • narcotic pain relievers (e.g., codeine)
  • psychiatric medicines (e.g., phenothiazines such as chlorpromazine)
  • sleep medications
  • sedatives
  • tranquilizers

Report other drugs which affect the heart rhythm (QTc prolongation), such as:

  • dofetilide
  • pimozide
  • sotalol
  • quinidine
  • procainamide
  • sparfloxacin
  • water pills (diuretics such as furosemide or hydrochlorothiazide)

Do not start or stop any medicine without medical provider's or pharmacist's approval.


Symptoms of overdose may include

  • irregular heartbeat
  • fainting
  • severe dizziness or lightheadedness

If overdose is suspected, contact your local poison control center (1-800-222-1222) or emergency room (911) immediately.


Do not share Paxil with others. Your doctor may do laboratory and/or medical tests to monitor your progress.


If you miss a dose, take it as soon as you remember. If it is close to the time of the next dose, do not take the missed dose. Then resume your usual dosing schedule. Do not take a double dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) Avoid away from light and moisture. Do not store in the bathroom.


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The information found on this website is informational only. It is not intended to be a substitute for doctor or other medical care provider advise. Do not use this information to diagnose or treat a disease or health problem or to prescribe any medication. See your doctor promptly if you are sick or think you have a disease. Read and carefully follow directions found in the product packaging. We make no claim as to the accuracy or appropriateness of the information found on this website.

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