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BUPROPION DRUG INFORMATION, ABOUT BUPROPION HCL

GENERIC WELLBUTRIN®, GENERIC ZYBAN®: Bupropion (byou-PRO-pee-on)

WHAT IS BUPROPION?

This Bupropion hydrochloride is used to treat depression.

HOW TO USE

Bupropion may cause stomach upset. If it does, take with food.

Take your bupropion dosage at regularly scheduled times each day.

Take only what is prescribed and carefully follow your doctor's instructions. Taking too much bupropion will increase the risk of seizures.

Do not stop taking bupropion without speaking your doctor.

Bupropion may cause sleeplessness when you first start taking it. Therefore, it is not recommended to be taken near bedtime.

It may take 4 weeks or more before the full effects of bupropion are noticed.

BUPROPION SIDE EFFECTS

Although it is generally well tolerated, the following bupropion side affects should be reported to your doctor if they continue or worsen:

• anxiety
• blurred vision
• constipation
• dry mouth
• fatigue
• headache
• increased sweating
• nausea/vomiting

If any of these bupropion side effects occur, report to your doctor promptly:

• agitation
• unexplained weight loss or gain
• palpitations
• trouble sleeping

These bupropion side affects are unlikely. However, if they occur, report promptly:

• tremors
• decreased sex drive
• difficulty urinating
• drowsiness
• dizziness
• fainting
• mood changes
• slowed movements

These bupropion side effects are highly unlikely. However, if they occur, report promptly:

• fever
• mental problems
• muscle aches
• seizures
• yellowing of the eyes or skin

An allergic reaction to bupropion is unlikely, but if it occurs, seek medical attention immediately. Symptoms of an allergic reaction may include:

• trouble breathing
• rash
• itching
• swelling
• severe dizziness.

If you notice other symptoms not listed above, contact your doctor or pharmacist.

PRECAUTIONS

Before taking bupropion, tell your doctor if you have:

• alcohol dependence
• allergies
• brain tumor
• head injury
• history of seizures
• heart disease
• diabetes
• liver disease
• kidney disease
• eating disorder
• the intent to quit smoking

Because bupropion may make you dizzy and affect coordination, do not drive or operate machinery until you know how it will affect you.

Drinking alcohol while taking bupropion can increase your risk of seizures. It is best to limit or avoid consuming alcoholic beverages. If you are a chronic alcohol users and suddenly stop while taking Bupropion, you may increase the risk of having seizures.

It is not wise to suddenly stop taking certain tranquilizers (e.g., diazepam, chlordiazepoxide). Doing so may cause an increases seizure risk.

Elderly patients may find that they are more sensitive to the effects of bupropion.

BUPROPION and PREGNANCY

Before taking bupropion medication , tell your doctor if you are pregnant or trying to become pregnant.

BUPROPION and BREAST FEEDING

Bupropion passes into breast milk. Breast feeding while using bupropion is not recommended. Consult your doctor before breast-feeding.

BUPROPION DRUG INTERACTIONS

Before you buy bupropion online, tell your doctor about all prescription and nonprescription medicines you may take, especially:

• MAO inhibitors like:
  • furazolidone
  • isocarboxazid
  • linezolid
  • pargyline
  • phenelzine
  • selegiline
  • tranylcypromine
• adrenaline-like stimulants (for example, ephedrine)
• corticosteroids (for example, prednisone)
• levodopa
• products containing nicotine (for example, patches or gum).
• ritonavir
• sedatives

Some drugs increase the risk of seizures. Tell your doctor if you use any of them, like:

• isoniazid (INH)
• phenothiazines (for example, chlorpromazine)
• theophylline
• tricyclic antidepressants (for example, amitriptyline)

Limit your caffeine intake. Large amounts of caffeine can increase the risk of seizures while using bupropion medicine. Some prescription and nonprescription drugs contain caffeine. Check the labels for caffeine. You may ask your doctor or pharmacist.

Bupropion is an ingredient of a certain product used to help quit smoking contains. Do not take that product while using bupropion.

Do not start or stop bupropion or any medicine without consulting your doctor or pharmacist.

BUPROPION OVERDOSE

If an overdose is suspected, contact your local poison control center (1-800-222-1222) or emergency room (911) immediately.

Possible symptoms of overdose:

• hallucinations
• loss of consciousness
• seizures
• rapid heart rate

NOTES

Do not give your bupropion drugs to anyone else to take.

MISSED DOSE

Take your missed dose as soon as you remember it, but not within 4 hours of the next dose. If it is within 4 hours of the next dose, skip the missed dose and resume your regular schedule. Do not take a double dose.

STORAGE

Store bupropion at room temperature. Avoid moisture and sunlight. Do not store bupropion in the bathroom.

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